SCHEMBL18174703

SCHEMBL18174703

Cc1ccncc1-c1ccc(-c2c3ccccc3c(-c3ccc(-c4cccnc4)cc3)c3ccccc23)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 5/20 0.48
CYP17A1 P05093 5/20 0.48
DHODH Q02127 1/20 0.46
CYP2A6 P11509 4/20 0.44
CYP3A4 P08684 2/20 0.44
ALDH1A1 P00352 1/20 0.44
KIF11 P52732 1/20 0.44
MKNK1 Q9BUB5 1/20 0.44
MKNK2 Q9HBH9 1/20 0.44
USP1 O94782 1/20 0.44
WDR48 Q8TAF3 1/20 0.44
CYP11B1 P15538 3/20 0.42
CYP11B2 P19099 3/20 0.42
CYP2E1 P05181 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2B6 P20813 1/20 0.42
CYP2C19 P33261 1/20 0.42
NPY5R Q15761 1/20 0.42
PIK3CA P42336 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15161087 0.92 CYP17A1 (0.47) CYP1A2CYP17A1DHODHCYP2A6CYP3A4
SCHEMBL18174554 0.91 DHODH (0.52) CYP1A2CYP17A1DHODHCYP11B1CYP11B2
SCHEMBL18174773 0.90 DHODH (0.49) CYP1A2CYP17A1DHODHCYP2A6CYP3A4
SCHEMBL18174656 0.90 SLC2A1 (0.49) CYP1A2CYP17A1DHODHCYP2A6CYP3A4
SCHEMBL15160912 0.89 CYP17A1 (0.51) CYP1A2CYP17A1DHODHCYP11B1CYP11B2
SCHEMBL18174661 0.89 DHODH (0.44) CYP1A2CYP17A1DHODHCYP11B1CYP11B2
SCHEMBL15160913 0.88 SLC2A1 (0.50) CYP1A2CYP17A1DHODHCYP2A6CYP3A4
SCHEMBL15161064 0.86 DHODH (0.50) CYP1A2CYP17A1DHODHCYP11B1CYP11B2
SCHEMBL29579846 0.86 DHODH (0.50) CYP1A2CYP17A1DHODHCYP11B1CYP11B2
SCHEMBL15977551 0.86 DHODH (0.50) CYP1A2CYP17A1DHODHCYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed