SCHEMBL18174842

SCHEMBL18174842

c1ccc(N(c2ccccc2)c2ccc(-c3ccc4ccc5c(-c6ccc(N(c7ccc8ccccc8c7)c7ccc8ccccc8c7)cc6)ccc6ccc3c4c65)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSTP1 P09211 1/20 0.35
CYP1A2 P05177 4/20 0.34
ALDH1A1 P00352 4/20 0.34
MAPT P10636 2/20 0.34
CYP2C9 P11712 2/20 0.34
CYP2C19 P33261 2/20 0.34
KDM4E B2RXH2 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
ERBB2 P04626 1/20 0.34
FYN P06241 1/20 0.34
MAOA P21397 1/20 0.34
ACHE P22303 1/20 0.34
AHR P35869 1/20 0.34
ACMSD Q8TDX5 1/20 0.33
HPGD P15428 3/20 0.32
HSD17B10 Q99714 2/20 0.32
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12433896 1.00 GSTP1 (0.35) GSTP1CYP1A2ALDH1A1MAPTCYP2C9
SCHEMBL18174851 0.97 CYP1A2 (0.39) GSTP1CYP1A2ALDH1A1MAPTCYP2C9
SCHEMBL17933142 0.94 GSTP1 (0.35) GSTP1CYP1A2ALDH1A1MAPTCYP2C9
SCHEMBL18174852 0.94 CYP1A2 (0.41) GSTP1CYP1A2ALDH1A1CYP3A4TDP1
SCHEMBL18079875 0.93 CYP1A2 (0.40) GSTP1CYP1A2ALDH1A1MAPTCYP2C9
SCHEMBL17264014 0.93 GSTP1 (0.31) GSTP1CYP1A2ALDH1A1MAPTCYP2C9
SCHEMBL10028986 0.93 GSTP1 (0.31) GSTP1CYP1A2ALDH1A1MAPTCYP2C9
SCHEMBL17264045 0.93 GSTP1 (0.31) GSTP1CYP1A2ALDH1A1MAPTCYP2C9
SCHEMBL556217 0.93 GSTP1 (0.31) GSTP1CYP1A2ALDH1A1MAPTCYP2C9
SCHEMBL557051 0.92 GSTP1 (0.30) GSTP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478752-B2 Organic light-emitting diode comprising amine-based compounds and pyrene-based compounds SAMSUNG DISPLAY CO., LTD. (KR) 2016-10-25 US disclosed
US-9478752-B2 Organic light-emitting diode comprising amine-based compounds and pyrene-based compounds SAMSUNG DISPLAY CO., LTD. (KR) 2016-10-25 US disclosed