SCHEMBL18174846

SCHEMBL18174846

c1ccc(-n2c(-c3ccc(-c4cc5cccc6ccc7cccc4c7c65)cc3)nc3ccccc32)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.49
ESR2 Q92731 1/20 0.49
GRIA1 P42261 1/20 0.45
CACNG8 Q8WXS5 1/20 0.45
CACNG2 Q9Y698 1/20 0.45
RECQL P46063 1/20 0.43
HTT P42858 2/20 0.43
MAPK1 P28482 1/20 0.43
HDAC1 Q13547 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
KMT2A Q03164 3/20 0.42
GAA P10253 2/20 0.42
MEN1 O00255 2/20 0.42
ALDH1A1 P00352 8/20 0.41
LMNA P02545 1/20 0.41
PTGS2 P35354 1/20 0.41
HSP90AA1 P07900 1/20 0.41
MAPT P10636 1/20 0.41
PTGER4 P35408 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25112785 0.95 ESR1 (0.47) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL25112895 0.93 ESR1 (0.49) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL25112787 0.92 ESR1 (0.52) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL25112939 0.92 ESR1 (0.48) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL10041759 0.90 ESR1 (0.51) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL25112903 0.89 ESR1 (0.54) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL15446900 0.89 ESR1 (0.51) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL9976878 0.89 ESR1 (0.50) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL12144513 0.88 RECQL (0.43) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL15446902 0.87 ESR1 (0.54) ESR1ESR2GRIA1CACNG8CACNG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478752-B2 Organic light-emitting diode comprising amine-based compounds and pyrene-based compounds SAMSUNG DISPLAY CO., LTD. (KR) 2016-10-25 US disclosed
US-9478752-B2 Organic light-emitting diode comprising amine-based compounds and pyrene-based compounds SAMSUNG DISPLAY CO., LTD. (KR) 2016-10-25 US disclosed