SCHEMBL181751

SCHEMBL181751

C=C(C)C(=O)OCCCN=C=O

nearest known ligand 0.53

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.53
THRB P10828 1/20 0.46
POLB P06746 1/20 0.41
APEX1 P27695 1/20 0.41
HTT P42858 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
ALDH1A1 P00352 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL633702 0.95 TSHR (0.56) TSHRTHRBPOLBAPEX1HTT
SCHEMBL2483259 0.93 TSHR (0.59) TSHRTHRBPOLBAPEX1HTT
SCHEMBL2480778 0.93 TSHR (0.59) TSHRTHRBPOLBAPEX1HTT
SCHEMBL1527497 0.93 TSHR (0.59) TSHRTHRBPOLBAPEX1HTT
SCHEMBL2481162 0.93 TSHR (0.59) TSHRTHRBPOLBAPEX1HTT
SCHEMBL181712 0.93 TSHR (0.59) TSHRTHRBPOLBAPEX1HTT
SCHEMBL1850039 0.93 TSHR (0.59) TSHRTHRBPOLBAPEX1HTT
SCHEMBL17780845 0.93 TSHR (0.59) TSHRTHRBPOLBAPEX1HTT
SCHEMBL5362558 0.93 TSHR (0.59) TSHRTHRBPOLBAPEX1HTT
SCHEMBL1304140 0.93 TSHR (0.59) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 877 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114736579-B Fluorocarbon coating, preparation method thereof and multilayer film application 安徽屹珹新材料科技有限公司 2024-05-10 CN claimed
EP-4321549-A1 LOW VISCOSITY ASPARTATE TERMINATED PREPOLYMERS FOR ADHESIVE APPLICATIONS Covestro LLC (US) 2024-02-14 EP claimed
WO-2023249854-A1 LOW VISCOSITY ASPARTATE TERMINATED PREPOLYMERS FOR ADHESIVE APPLICATIONS COVESTRO LLC (US) 2023-12-28 WO claimed
US-20230416444-A1 LOW VISCOSITY ASPARTATE TERMINATED PREPOLYMERS FOR ADHESIVE APPLICATIONS COVESTRO LLC 2023-12-28 US claimed
US-20220154043-A1 ADHESIVE COMPOSITION FOR DICING FILM, DICING FILM AND DICING DIE BOND FILM LG CHEM, LTD. (KR) 2022-05-19 US claimed
US-20180179312-A1 THERMOPLASTIC RESIN COMPOSITION AND MOLDING PRODUCT MADE THEREFROM CHI MEI CORPORATION (TW) 2018-06-28 US claimed
EP-2558441-B1 PROCESS FOR PRODUCING ISOCYANATES 3M INNOVATIVE PROPERTIES CO (US) 2018-05-30 EP claimed
US-9701863-B2 Self-renewing hydrophilic organic coatings EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2017-07-11 US claimed
CN-106795397-A Adhesive composition for touch screen panel, optical adhesive film, and touch screen panel 株式会社LG化学 2017-05-31 CN claimed
US-20160046829-A1 SELF-RENEWING HYDROPHILIC ORGANIC COATINGS CRESTLINE DIRECT FINANCE, L.P. 2016-02-18 US claimed
US-5334681-A High oxygen permeability; resiliency, flexibility; wettability; biocompatibility CIBA-GEIGY CORPORATION (US) 1994-08-02 US claimed
US-5213934-A Core of colorant and binder grafted to polymeric shell XEROX CORPORATION (US) 1993-05-25 US claimed
EP-0523723-A1 Resin composition MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-01-20 EP claimed
EP-0493320-A2 Fluorine and/or Silicone containing poly(alkylene-oxide)-block copolymer hydrogels and contact lenses thereof CIBA-GEIGY AG (CH) 1992-07-01 EP claimed
US-5115056-A FLUORINE AND/OR SILICONE CONTAINING POLY(ALKYLENE-OXIDE)-BLOCK COPOLYMERS AND CONTACT LENSES THEREOF CIBA-GEIGY CORPORATION (US) 1992-05-19 US claimed
US-5075384-A Air-drying, curable protective coatings comprising an allyl alcohol-styrene copolymer carbamylated by an unsaturated isocyanate, an acrylic monomer and an allyl monomer; gloss; toughness MONSANTO (US) 1991-12-24 US claimed
US-5049623-A Solvent resistance, high gloss MONSANTO COMPANY (US) 1991-09-17 US claimed
US-5030696-A Air- or heat-curable protective coatings of unsaturated isocyanate-modified styrene-allyl alcohol copolymer, an acrylic compound and an allyl compound; furniture; toughness MONSANTO COMPANY (US) 1991-07-09 US claimed
EP-0425436-A2 Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof CIBA-GEIGY AG (CH) 1991-05-02 EP claimed
US-5010141-A Heat- or UV-curable acrylic resins; coatings; films; biocompatible, water-swelling, oxygen-permeable contact lenses CIBA-GEIGY CORPORATION (US) 1991-04-23 US claimed