SCHEMBL18175601

SCHEMBL18175601

CCCCCCOc1ccc(C(=O)Oc2ccc(C3=CCC(c4ccc(OCCCC)c(F)c4F)CC3)c(F)c2F)c(F)c1F

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 3/20 0.35
CNR2 P34972 3/20 0.35
THRB P10828 3/20 0.34
PTPN1 P18031 2/20 0.33
CYP2C9 P11712 1/20 0.33
SCN9A Q15858 1/20 0.33
THRA P10827 2/20 0.32
S1PR1 P21453 5/20 0.31
S1PR3 Q99500 4/20 0.31
S1PR5 Q9H228 4/20 0.31
PTPN11 Q06124 3/20 0.31
MEN1 O00255 1/20 0.31
NR1I2 O75469 1/20 0.31
LMNA P02545 1/20 0.31
CHRM2 P08172 1/20 0.31
CYP3A4 P08684 1/20 0.31
ADRA2A P08913 1/20 0.31
MAPT P10636 1/20 0.31
OPRK1 P41145 1/20 0.31
HTR2B P41595 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18175657 1.00 CNR1 (0.35) CNR1CNR2THRBPTPN1CYP2C9
SCHEMBL18175668 0.97 CNR1 (0.34) CNR1CNR2THRBPTPN1CYP2C9
SCHEMBL15381756 0.97 SCN9A (0.34) CNR1CNR2CYP2C9SCN9ACRBN
SCHEMBL15381738 0.97 SCN9A (0.34) CNR1CNR2CYP2C9SCN9ACRBN
SCHEMBL18175604 0.97 CNR2 (0.33) CNR1CNR2THRBPTPN1CYP2C9
SCHEMBL18175624 0.97 CNR2 (0.33) CNR1CNR2THRBPTPN1CYP2C9
SCHEMBL15381621 0.96 SCN9A (0.33) CNR1CNR2CYP2C9SCN9AMEN1
SCHEMBL15381828 0.96 SCN9A (0.33) CNR1CNR2CYP2C9SCN9AMEN1
SCHEMBL11933502 0.95 CNR1 (0.33) CNR1CNR2THRBPTPN1CYP2C9
SCHEMBL11933546 0.95 CNR1 (0.33) CNR1CNR2THRBPTPN1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479162-B1 LIQUID CRYSTALLINE COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC CORP (JP) 2016-10-26 EP disclosed