SCHEMBL18175956

SCHEMBL18175956

C=CCOC(=O)C(O)C(O)C(=O)OCCC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.44
TDP1 Q9NUW8 2/20 0.41
HPGD P15428 1/20 0.37
HCAR2 Q8TDS4 1/20 0.37
CYP3A4 P08684 1/20 0.35
GRM2 Q14416 1/20 0.34
GRM3 Q14832 1/20 0.34
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
MAPT P10636 1/20 0.33
CACNA1B Q00975 1/20 0.33
APBA1 Q02410 1/20 0.33
ALDH1A1 P00352 3/20 0.32
HTT P42858 1/20 0.32
LMNA P02545 1/20 0.32
ATM Q13315 1/20 0.31
HSD17B10 Q99714 1/20 0.31
ESR1 P03372 1/20 0.31
CHRM1 P11229 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12189520 0.90 TDP1 (0.41) TSHRTDP1HPGDHCAR2CYP3A4
SCHEMBL167949 0.85 CYP3A4 (0.43) TSHRTDP1CYP3A4CA1CA2
SCHEMBL6414229 0.83 HCAR2 (0.43) TSHRTDP1HPGDHCAR2ALDH1A1
SCHEMBL2866836 0.83 HCAR2 (0.43) TSHRTDP1HPGDHCAR2ALDH1A1
SCHEMBL8636453 0.83 HCAR2 (0.43) TSHRTDP1HPGDHCAR2ALDH1A1
SCHEMBL14672059 0.83 HCAR2 (0.43) TSHRTDP1HPGDHCAR2ALDH1A1
Ammonia Solution, Strong SCHEMBL28223082 0.81 CYP3A4 (0.41) TSHRTDP1CYP3A4CA1CA2
Ammonia Solution, Strong SCHEMBL21219091 0.81 HCAR2 (0.41) TSHRTDP1HCAR2ALDH1A1HTT
SCHEMBL996494 0.79 TSHR (0.51) TSHRTDP1HPGDHCAR2ATM
SCHEMBL167950 0.78 TSHR (0.43) TSHRTDP1CYP3A4CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3086396-A1 NONAQUEOUS ELECTROLYTE, CAPACITOR DEVICE USING SAME, AND CARBOXYLIC ACID ESTER COMPOUND USED IN SAME UBE Industries, Ltd. (JP) 2016-10-26 EP disclosed