Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 18/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23316970 | 0.82 | RPS6KB1 (0.84) | RPS6KB1LMNA | |
| SCHEMBL20445802 | 0.82 | RPS6KB1 (1.00) | RPS6KB1 | |
| SCHEMBL18176362 | 0.80 | RPS6KB1 (0.51) | RPS6KB1 | |
| SCHEMBL18176281 | 0.80 | RPS6KB1 (0.69) | RPS6KB1 | |
| SCHEMBL18176402 | 0.80 | RPS6KB1 (0.69) | RPS6KB1 | |
| SCHEMBL18171883 | 0.79 | RPS6KB1 (0.71) | RPS6KB1 | |
| SCHEMBL780561 | 0.78 | PDGFRB (0.53) | RPS6KB1LMNAPDGFRBPDGFRA | |
| Hydrochloric Acid SCHEMBL16161463 | 0.77 | PDGFRB (0.52) | RPS6KB1LMNAPDGFRBPDGFRA | |
| SCHEMBL780356 | 0.76 | PDGFRB (0.56) | PDGFRBPDGFRA | |
| SCHEMBL18176396 | 0.74 | RPS6KB1 (0.72) | RPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016170163-A1 | SUBSTITUTED QUINOXALINES AND BENZOTRIAZINE P70S6 KINASE INHIBITORS | SENTINEL ONCOLOGY LIMITED (GB) | 2016-10-27 | — | — | WO | disclosed |