Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 11/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 2/20 | 0.34 |
| ▸ | RXRB | P28702 | 2/20 | 0.34 |
| ▸ | RXRG | P48443 | 2/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18178120 | 0.92 | MRGPRX4 (0.42) | MRGPRX4FFAR1FFAR4S1PR1HPGD | |
| SCHEMBL18178084 | 0.91 | MRGPRX4 (0.41) | MRGPRX4FFAR1FFAR4S1PR1HPGD | |
| SCHEMBL18178516 | 0.90 | MRGPRX4 (0.39) | MRGPRX4FFAR1FFAR4S1PR1HPGD | |
| SCHEMBL18178425 | 0.89 | MRGPRX4 (0.37) | MRGPRX4FFAR1FFAR4HPGDRXRA | |
| SCHEMBL18178086 | 0.87 | MRGPRX4 (0.43) | MRGPRX4FFAR1FFAR4S1PR1HPGD | |
| SCHEMBL18178058 | 0.86 | MRGPRX4 (0.47) | MRGPRX4FFAR1HPGDPTGER1PTGER4 | |
| SCHEMBL18178089 | 0.86 | MRGPRX4 (0.43) | MRGPRX4S1PR1PTGER1 | |
| SCHEMBL18178121 | 0.86 | MRGPRX4 (0.46) | MRGPRX4FFAR1FFAR4HPGDPTGER1 | |
| SCHEMBL18178219 | 0.86 | MRGPRX4 (0.37) | MRGPRX4FFAR1FFAR4PTGER1 | |
| SCHEMBL18178092 | 0.85 | MRGPRX4 (0.42) | MRGPRX4S1PR1HPGDRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9573904-B2 | Aromatic compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-02-21 | — | — | US | disclosed |
| US-20160311775-A1 | AROMATIC COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160311775-A1 | AROMATIC COMPOUND AND USE THEREOF | ZCCHC8, CBR3, CBX8 | MRGPRX4 167/4885FFAR1 2736/4885FFAR4 2485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.