Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29384730 | 0.90 | MAPT (0.50) | MAPTNPC1RAB9ATDP1MAPK1 | |
| SCHEMBL15627463 | 0.90 | MAPT (0.50) | MAPTNPC1RAB9ATDP1MAPK1 | |
| SCHEMBL17787267 | 0.88 | CA12 (0.46) | MAPTNPC1RAB9ATDP1MAPK1 | |
| SCHEMBL23259594 | 0.86 | MAPT (0.46) | MAPTNPC1RAB9ATDP1MAPK1 | |
| SCHEMBL22974892 | 0.86 | MAPT (0.46) | MAPTNPC1RAB9ATDP1MAPK1 | |
| SCHEMBL16222316 | 0.85 | MAPT (0.48) | MAPTNPC1RAB9ATDP1MAPK1 | |
| SCHEMBL24891223 | 0.83 | MAPT (0.43) | MAPTNPC1RAB9ATDP1MAPK1 | |
| SCHEMBL29141580 | 0.82 | MAPT (0.40) | MAPTNPC1RAB9ATDP1MAPK1 | |
| SCHEMBL16997052 | 0.81 | MAPT (0.48) | MAPTNPC1RAB9ATDP1MAPK1 | |
| SCHEMBL17787265 | 0.81 | MAPT (0.41) | MAPTNPC1RAB9ATDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160312403-A1 | DISPERSE DYE COMPOSITION, DISPERSE DYE AND PREPARATION METHOD AND USE THEREOF | ZHEJIANG RUNTU CO., LTD. (CN) | 2016-10-27 | — | — | US | disclosed |
| US-20160312403-A1 | DISPERSE DYE COMPOSITION, DISPERSE DYE AND PREPARATION METHOD AND USE THEREOF | ZHEJIANG RUNTU CO., LTD. (CN) | 2016-10-27 | — | — | US | disclosed |