Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | GSK3B | P49841 | 5/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18160148 | 0.96 | GSK3B (0.55) | KMT2AMEN1MAPTLMNASMN1; SMN2 | |
| SCHEMBL18180611 | 0.96 | GSK3B (0.55) | KMT2AMEN1MAPTLMNASMN1; SMN2 | |
| SCHEMBL7915055 | 0.85 | MEN1 (0.65) | KMT2AMEN1MAPTLMNASMN1; SMN2 | |
| SCHEMBL7915056 | 0.85 | MEN1 (0.65) | KMT2AMEN1MAPTLMNASMN1; SMN2 | |
| SCHEMBL29284806 | 0.80 | KMT2A (0.57) | KMT2AMEN1MAPTLMNASMN1; SMN2 | |
| SCHEMBL30950638 | 0.80 | KMT2A (0.57) | KMT2AMEN1MAPTLMNASMN1; SMN2 | |
| SCHEMBL19670136 | 0.77 | IDO1 (0.68) | KMT2AMEN1MAPTLMNAGSK3B | |
| SCHEMBL18160194 | 0.77 | MAPT (0.68) | KMT2AMEN1MAPTLMNASMN1; SMN2 | |
| SCHEMBL18160189 | 0.77 | MEN1 (0.50) | KMT2AMEN1MAPTLMNASMN1; SMN2 | |
| SCHEMBL19670109 | 0.75 | KMT2A (0.47) | KMT2AMEN1MAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016172193-A1 | ANTIBIOTIC SENSITIVITY-RESTORING AND PHOTOSENSITIVE AGENTS | NEW MEXICO TECH RESEARCH FOUNDATION (US) | 2016-10-27 | — | — | WO | disclosed |