Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18180868 | 0.86 | MAPT (0.36) | MAPTMEN1ALDH1A1KMT2ANPC1 | |
| SCHEMBL18180882 | 0.82 | FNTA (0.45) | MAPTMEN1ALDH1A1KMT2ANPC1 | |
| Grossheimin SCHEMBL1711489 | 0.80 | MAPT (0.34) | MAPTMEN1ALDH1A1KMT2ANPC1 | |
| Grossheimin SCHEMBL1711493 | 0.80 | MAPT (0.34) | MAPTMEN1ALDH1A1KMT2ANPC1 | |
| SCHEMBL18180867 | 0.80 | MEN1 (0.31) | MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL18180884 | 0.78 | MAPT (0.37) | MAPTMEN1ALDH1A1KMT2ANPC1 | |
| SCHEMBL18180873 | 0.74 | UBE2D3 (0.41) | MAPTMEN1ALDH1A1KMT2ANPC1 | |
| SCHEMBL18180878 | 0.74 | DYRK1A (0.40) | MAPTMEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL18180936 | 0.71 | — | — | |
| SCHEMBL18180866 | 0.70 | NPC1 (0.32) | MAPTNPC1HTTRAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016169573-A1 | SESQUITERPENE LACTONES AS POTENT AND BROAD SPECTRUM ANTIVIRAL COMPOUNDS AGAINST ALL GENOTYPES OF HEPATITIS C VIRUS (HCV) | ELSEBAI MAHMOUD FAHMI (EG) | 2016-10-27 | — | — | WO | disclosed |