Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 2/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 8/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 3/20 | 0.33 |
| ▸ | MMP2 | P08253 | 3/20 | 0.33 |
| ▸ | MMP7 | P09237 | 3/20 | 0.33 |
| ▸ | MMP14 | P50281 | 3/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.33 |
| ▸ | MET | P08581 | 2/20 | 0.33 |
| ▸ | BCL2 | P10415 | 2/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.33 |
| ▸ | SNCA | P37840 | 2/20 | 0.33 |
| ▸ | PGD | P52209 | 2/20 | 0.33 |
| ▸ | PKMYT1 | Q99640 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18180878 | 0.77 | DYRK1A (0.40) | SERPINE1DYRK1AIGF1RBACE1MMP2 | |
| SCHEMBL18180932 | 0.75 | MEN1 (0.31) | MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL18180921 | 0.72 | — | — | |
| SCHEMBL18180936 | 0.72 | — | — | |
| SCHEMBL18180877 | 0.69 | MEN1 (0.30) | MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL18180916 | 0.69 | UBE2D3 (0.36) | HSP90AB1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL10307515 | 0.68 | — | — | |
| SCHEMBL12459119 | 0.64 | CYP3A4 (0.32) | CYP3A4 | |
| SCHEMBL18180873 | 0.62 | UBE2D3 (0.41) | KDM4EMEN1MAPTRECQLKMT2A | |
| SCHEMBL18180886 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016169573-A1 | SESQUITERPENE LACTONES AS POTENT AND BROAD SPECTRUM ANTIVIRAL COMPOUNDS AGAINST ALL GENOTYPES OF HEPATITIS C VIRUS (HCV) | ELSEBAI MAHMOUD FAHMI (EG) | 2016-10-27 | — | — | WO | disclosed |