Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 13/20 | 0.73 |
| ▸ | MAOB | P27338 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18182597 | 1.00 | KDM1A (0.73) | KDM1AMAOBKMT2AL3MBTL1NFKB1 | |
| SCHEMBL18182985 | 1.00 | KDM1A (0.73) | KDM1AMAOBKMT2AL3MBTL1NFKB1 | |
| SCHEMBL18182141 | 1.00 | KDM1A (0.73) | KDM1AMAOBKMT2AL3MBTL1NFKB1 | |
| SCHEMBL18182633 | 1.00 | KDM1A (0.73) | KDM1AMAOBKMT2AL3MBTL1NFKB1 | |
| SCHEMBL18182674 | 0.87 | KDM1A (0.56) | KDM1AMAOBKMT2AL3MBTL1NFKB1 | |
| SCHEMBL18181821 | 0.86 | KDM1A (0.64) | KDM1AMAOBKMT2AL3MBTL1DRD2 | |
| SCHEMBL18183001 | 0.86 | KDM1A (0.64) | KDM1AMAOBKMT2AL3MBTL1DRD2 | |
| SCHEMBL18181896 | 0.86 | KDM1A (0.64) | KDM1AMAOBKMT2AL3MBTL1DRD2 | |
| SCHEMBL21088918 | 0.85 | KDM1A (0.55) | KDM1AMAOBKMT2AL3MBTL1NFKB1 | |
| SCHEMBL18173026 | 0.85 | KDM1A (0.86) | KDM1AMAOBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016172496-A1 | LSD1 INHIBITORS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS, INC. (US) | 2016-10-27 | — | — | WO | disclosed |