SCHEMBL1818422

SCHEMBL1818422

O=C(NCCC1CC1)c1ccc(N2CCC(C(=O)c3ccccc3C(F)(F)F)CC2)nn1

nearest known ligand 0.77

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SCD O00767 15/20 0.77
DCTPP1 Q9H773 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1378991 0.87 SCD (1.00) SCDDCTPP1
SCHEMBL1379639 0.86 SCD (0.85) SCDDCTPP1
SCHEMBL1813870 0.86 SCD (0.68) SCDDCTPP1
SCHEMBL1817527 0.84 SCD (0.70) SCDDCTPP1
SCHEMBL1378674 0.84 SCD (0.93) SCDDCTPP1
SCHEMBL1813574 0.83 SCD (0.71) SCDDCTPP1
SCHEMBL1816080 0.83 SCD (0.69) SCDDCTPP1
SCHEMBL14542704 0.83 SCD (0.58) SCDDCTPP1
SCHEMBL1817135 0.83 SCD (0.68) SCD
SCHEMBL1815448 0.83 SCD (0.68) SCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7951805-B2 Heterocyclic derivatives and their use as mediators of stearoyl-CoA desaturase XENON PHARMACEUTICALS INC. (CA) 2011-05-31 US claimed
US-7951805-B2 Heterocyclic derivatives and their use as mediators of stearoyl-CoA desaturase XENON PHARMACEUTICALS INC. (CA) 2011-05-31 US disclosed