Butyric Acid

Butyric Acid

SCHEMBL1818653

CCCC(=O)[O-].C[N+](C)(C)O

nearest known ligand 0.78

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Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 2/20 0.78
HDAC3 O15379 2/20 0.78
HDAC1 Q13547 2/20 0.78
HDAC2 Q92769 2/20 0.78
HDAC8 Q9BY41 2/20 0.78
CA1 P00915 1/20 0.52
CES2 O00748 1/20 0.50
CES1 P23141 1/20 0.50
BBOX1 O75936 8/20 0.48
NFKB1 P19838 1/20 0.43
GPR84 Q9NQS5 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butyric Acid SCHEMBL109152 0.92 FFAR3 (0.82) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL107100 0.85
Butyric Acid SCHEMBL2587931 0.85 FFAR3 (0.93) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL1176373 0.85 FFAR3 (0.93) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL10908702 0.85 FFAR3 (0.93) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL11441641 0.85 FFAR3 (0.93) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL9800297 0.85 FFAR3 (0.93) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL4292004 0.85 FFAR3 (1.00) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL1330878 0.85
Butyric Acid SCHEMBL11419652 0.85 FFAR3 (0.93) FFAR3HDAC3HDAC1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9050378-B2 N2S2 chelate-targeting ligand conjugates BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2015-06-09 US disclosed
CN-103494213-A Preparation method of fat-burning low-calorie total-nutrient meal replacement preparation FIRST AFFILIATED HOSPITAL SUN YAT SEN UNIV 2014-01-08 CN disclosed
EP-2316493-A2 Ethylenedicysteine (EC)-drug conjugates, compositions and methods for tissue specific disease imaging Board of Regents, The University of Texas System (US) 2011-05-04 EP disclosed
US-20050232911-A1 Prevention and treatment of metabolic abnormalities associated with excess intramyocellular lipid SCHREIBER BRIAN D 2005-10-20 US disclosed
US-20050129619-A1 N2S2 chelate-targeting ligand conjugates BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2005-06-16 US disclosed
WO-2004084885-A1 COMPOSITIONS FOR THE IMPROVEMENT OF OBESITY AMOREPACIFIC CORPORATION (KR) 2004-10-07 WO disclosed
US-20040166058-A1 Ethylenedicysteine (EC)-drug conjugates, compositions and methods for tissue specific disease imaging BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2004-08-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040166058-A1 Ethylenedicysteine (EC)-drug conjugates, compositions and methods for tissue specific disease imaging TEK, TIE1, CD40 FFAR3 1937/4885HDAC3 3581/4885HDAC1 3940/4885
US-20050129619-A1 N2S2 chelate-targeting ligand conjugates TYMS, CCNT2, TEK FFAR3 2121/4885HDAC3 3113/4885HDAC1 2753/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.