SCHEMBL181893

SCHEMBL181893

Cc1ccnc(-c2cc(C)ccn2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 2/20 1.00
CCR5 P51681 2/20 1.00
CCR8 P51685 2/20 1.00
METAP2 P50579 1/20 0.63
UHRF1 Q96T88 1/20 0.62
CYP2A6 P11509 1/20 0.57
KDM4E B2RXH2 2/20 0.56
NOS2 P35228 2/20 0.56
MEN1 O00255 1/20 0.56
NOS3 P29474 1/20 0.56
NOS1 P29475 1/20 0.56
KMT2A Q03164 1/20 0.56
PLAU P00749 1/20 0.45
GRIN2D O15399 1/20 0.43
GRIN3B O60391 1/20 0.43
GRIN1 Q05586 1/20 0.43
GRIN2A Q12879 1/20 0.43
GRIN2B Q13224 1/20 0.43
GRIN2C Q14957 1/20 0.43
GRIN3A Q8TCU5 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29397106 1.00 CCR1 (1.00) CCR1CCR5CCR8METAP2UHRF1
SCHEMBL2258309 0.97 CCR1 (0.94) CCR1CCR5CCR8METAP2UHRF1
Hydrochloric Acid SCHEMBL9639295 0.97 CCR1 (0.94) CCR1CCR5CCR8METAP2UHRF1
SCHEMBL31482991 0.97 CCR1 (0.94) CCR1CCR5CCR8METAP2UHRF1
SCHEMBL6820852 0.97 CCR1 (0.94) CCR1CCR5CCR8METAP2UHRF1
SCHEMBL6820765 0.97 CCR1 (0.94) CCR1CCR5CCR8METAP2UHRF1
Hydrochloric Acid SCHEMBL5549447 0.97 CCR1 (0.94) CCR1CCR5CCR8METAP2UHRF1
SCHEMBL31482988 0.97 CCR1 (0.94) CCR1CCR5CCR8METAP2UHRF1
SCHEMBL15664136 0.97 CCR1 (0.94) CCR1CCR5CCR8METAP2UHRF1
SCHEMBL32670845 0.97 CCR1 (0.94) CCR1CCR5CCR8METAP2UHRF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3212 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137312-A1 MEASUREMENT OF GLUCOSE NEAR AN INSULIN DELIVERY CATHETER BY MINIMIZING THE ADVERSE EFFECTS OF INSULIN PRESERVATIVES: ALTERNATIVE LIGANDS AND REDOX MEDIATOR METALS PACIFIC DIABETES TECH INC (US) 2026-05-21 US claimed
US-12630725-B2 Color enhancement utilizing up converters and/or down converters IMMUNOLIGHT, LLC (US) 2026-05-19 US claimed
US-12616848-B2 Energy augmentation structures, energy emitters or energy collectors containing the same, and their use in solar cells and other energy conversion devices IMMUNOLIGHT, LLC (US) 2026-05-05 US claimed
US-12611504-B2 Methods and systems for insulin delivery and glucose measurement Pacific Diabetes Technologies, Inc. (US) 2026-04-28 US claimed
EP-4727953-A2 ACCELERATED MARKING OF 5-FORMYL CYTOSINE AND USE IN NUCLEIC ACID METHYLATION SEQUENCING F. Hoffmann-La Roche AG (CH) 2026-04-22 EP claimed
US-12495995-B2 Measurement of glucose near an insulin delivery catheter by minimizing the adverse effects of insulin preservatives: alternative ligands and redox mediator metals PACIFIC DIABETES TECHNOLOGIES, INC (US) 2025-12-16 US claimed
US-20250375458-A1 COMPOSITIONS AND METHODS TO COMBAT MULTIDRUG-RESISTANT AND PERSISTENT T-CELL-MEDIATED, ONCOLOGICAL AND INFECTIOUS DISEASES THERALASE TECH INC (CA) 2025-12-11 US claimed
US-20250375511-A1 METHOD FOR TREATING CONDITIONS ASSOCIATED WITH HYPERPROLIFERATING CELLS COMPRISING COMBINED ADMINISTRATION OF INFECTIOUS AGENTS AND METAL CATIONS THERALASE TECH INC (CA) 2025-12-11 US claimed
US-20250362307-A1 PHOTOACTIVE ANTIBODY CONJUGATE LIAO JUNG CHI (TW) 2025-11-27 US claimed
US-12478734-B2 Methods and systems for insulin delivery and glucose measurement PACIFIC DIABETES TECHNOLOGIES INC. (US) 2025-11-25 US claimed
US-4954414-A Photosensitive composition containing a transition metal coordination complex cation and a borate anion and photosensitive materials employing the same THE MEAD CORPORATION (US) 1990-09-04 US claimed
EP-0096288-B1 PROCESS FOR THE ELECTROCHEMICAL HYDROGENATION OF NICOTIN-AMIDE-ADENINE DINUCLEOTIDE BASF Aktiengesellschaft (DE) 1985-08-21 EP claimed
EP-0075174-B1 PROCESS FOR THE PREPARATION OF 4-NITRODIPHENYL AMINES BAYER AG (DE) 1985-08-07 EP claimed
US-4526661-A Employing as electron carrier a metal complex having reduction potential which is not more negative than-1.3 volts at 10-70 degrees C. BASF AKTIENGESELLSCHAFT (US) 1985-07-02 US claimed
EP-0096288-A1 Process for the electrochemical hydrogenation of nicotin-amide-adenine dinucleotide BASF Aktiengesellschaft (DE) 1983-12-21 EP claimed
US-4404352-A ORGANOTIN COMPOUNDS AS CATALYST AND AMINES TO GIVE CURED COATINGS WITH PARTIALLY BLOCKED ISOCYANATES YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1983-09-13 US claimed
US-4404400-A REACTION OF AN ANILINE WITH A HALOGENONITROBENZENE BAYER AKTIENGESELLSCHAFT (DE) 1983-09-13 US claimed
EP-0075174-A1 Process for the preparation of 4-nitrodiphenyl amines BAYER AG (DE) 1983-03-30 EP claimed
EP-0073835-A1 PROCESS FOR PRODUCING POLYURETHANE POLYMER Yoshitomi Pharmaceutical Industries, Ltd. (JP) 1983-03-16 EP claimed
US-4086229-A Dinitrosyldihalo complexes of molybdenum or tungsten PHILLIPS PETROLEUM COMPANY (US) 1978-04-25 US claimed