Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 9/20 | 0.56 |
| ▸ | ACP1 | P24666 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.52 |
| ▸ | WNT3A | P56704 | 1/20 | 0.47 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.47 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.47 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18154386 | 0.90 | CSNK1D (0.56) | CSNK1DACP1HDAC3HDAC4HDAC1 | |
| SCHEMBL18154205 | 0.90 | CSNK1D (0.56) | CSNK1DACP1HDAC3HDAC4HDAC1 | |
| SCHEMBL18154206 | 0.90 | CSNK1D (0.56) | CSNK1DACP1HDAC3HDAC4HDAC1 | |
| SCHEMBL19852785 | 0.85 | CSNK1D (0.54) | CSNK1DACP1HDAC3HDAC4HDAC1 | |
| SCHEMBL18154189 | 0.85 | CSNK1D (0.54) | CSNK1DACP1HDAC3HDAC4HDAC1 | |
| SCHEMBL18154191 | 0.85 | CSNK1D (0.54) | CSNK1DACP1HDAC3HDAC4HDAC1 | |
| SCHEMBL18154214 | 0.83 | CSNK1D (0.59) | CSNK1DACP1HDAC3HDAC4HDAC1 | |
| SCHEMBL18154211 | 0.83 | CSNK1D (0.59) | CSNK1DACP1HDAC3HDAC4HDAC1 | |
| SCHEMBL31442476 | 0.83 | CSNK1D (0.59) | CSNK1DACP1HDAC3HDAC4HDAC1 | |
| SCHEMBL16445697 | 0.83 | ACP1 (0.61) | CSNK1DACP1HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3265448-A1 | RILUZOLE PRODRUGS AND THEIR USE | Biohaven Pharmaceutical Holding Company Ltd. (US) | 2018-01-10 | — | — | EP | disclosed |
| WO-2016140879-A9 | RILUZOLE PRODRUGS AND THEIR USE | BIOHAVEN PHARMACEUTICAL HOLDING COMPANY LTD. (US) | 2016-11-03 | — | — | WO | disclosed |