Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 5/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 5/20 | 0.44 |
| ▸ | ATR | Q13535 | 12/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15465183 | 1.00 | CYP4F2 (0.44) | CYP4F2CYP4A11ATRALDH1A1LMNA | |
| SCHEMBL15465184 | 1.00 | CYP4F2 (0.44) | CYP4F2CYP4A11ATRALDH1A1LMNA | |
| SCHEMBL15465690 | 0.99 | CYP4F2 (0.44) | CYP4F2CYP4A11ATRALDH1A1LMNA | |
| SCHEMBL15465688 | 0.99 | CYP4F2 (0.44) | CYP4F2CYP4A11ATRALDH1A1LMNA | |
| SCHEMBL20958953 | 0.83 | CYP4F2 (0.42) | CYP4F2CYP4A11ATRALDH1A1LMNA | |
| SCHEMBL24947689 | 0.80 | CYP4F2 (0.46) | CYP4F2CYP4A11ATRALDH1A1LMNA | |
| SCHEMBL20516647 | 0.80 | CYP4F2 (0.42) | CYP4F2CYP4A11ATRALDH1A1LMNA | |
| SCHEMBL20516645 | 0.80 | CYP4F2 (0.42) | CYP4F2CYP4A11ATRALDH1A1LMNA | |
| SCHEMBL23429555 | 0.80 | CYP4F2 (0.42) | CYP4F2CYP4A11ATRALDH1A1LMNA | |
| SCHEMBL20703898 | 0.73 | CYP4F2 (0.41) | CYP4F2CYP4A11ATRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2813491-B1 | CYCLOALKANE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2016-11-02 | — | — | EP | disclosed |