Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 13/20 | 0.42 |
| ▸ | SCN8A | Q9UQD0 | 8/20 | 0.38 |
| ▸ | SCN2B | O60939 | 4/20 | 0.38 |
| ▸ | SCN1B | Q07699 | 4/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 6/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15464984 | 1.00 | SCN9A (0.42) | SCN9ASCN8ASCN2BSCN1BSCN5A | |
| SCHEMBL16286826 | 0.91 | SCN9A (0.46) | SCN9ASCN8ASCN2BSCN1BSCN5A | |
| SCHEMBL15465951 | 0.83 | SCN9A (0.57) | SCN9ASCN8ASCN2BSCN1BSCN5A | |
| SCHEMBL15465636 | 0.81 | SCN9A (0.56) | SCN9ASCN8ASCN2BSCN1BSCN5A | |
| SCHEMBL15465775 | 0.80 | SCN9A (0.46) | SCN9ASCN8ASCN2BSCN1BSCN5A | |
| SCHEMBL15465507 | 0.78 | SCN9A (0.58) | SCN9ASCN8ASCN2BSCN1BSCN5A | |
| SCHEMBL36151836 | 0.76 | SCN8A (0.46) | SCN8ASCN1BSCN5ASCN1A | |
| SCHEMBL326999 | 0.76 | SCN8A (0.46) | SCN8ASCN1BSCN5ASCN1A | |
| SCHEMBL15465777 | 0.75 | SCN9A (0.58) | SCN9ASCN8ASCN2BSCN1BSCN5A | |
| SCHEMBL19627678 | 0.75 | SCN8A (0.63) | SCN8ASCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2813491-B1 | CYCLOALKANE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2016-11-02 | — | — | EP | disclosed |