Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 19/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720818 | 0.92 | TYK2 (0.42) | TYK2PDE4D | |
| SCHEMBL3720825 | 0.92 | TYK2 (0.42) | TYK2PDE4D | |
| SCHEMBL18192991 | 0.91 | TYK2 (0.49) | TYK2PDE4D | |
| SCHEMBL3718203 | 0.89 | TYK2 (0.46) | TYK2 | |
| SCHEMBL3718199 | 0.89 | TYK2 (0.46) | TYK2 | |
| SCHEMBL3779397 | 0.88 | TYK2 (0.52) | TYK2PDE4D | |
| SCHEMBL3779403 | 0.88 | TYK2 (0.52) | TYK2PDE4D | |
| SCHEMBL18193004 | 0.88 | TYK2 (0.41) | TYK2PDE4DTGFBR1TGFBR2 | |
| SCHEMBL13062355 | 0.88 | TYK2 (0.47) | TYK2PDE4D | |
| SCHEMBL3724153 | 0.88 | TYK2 (0.45) | TYK2PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240488-B1 | SUBSTITUTED IMIDAZOPYRIDAZINES USEFUL AS KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2016-11-02 | — | — | EP | claimed |