Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 11/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | MTOR | P42345 | 5/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PIK3C2B | O00750 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12499401 | 0.90 | PIK3CA (0.68) | PIK3CAMTORPIK3CGPIK3CDPIK3CB | |
| SCHEMBL12499391 | 0.88 | CYP1A2 (0.59) | PIK3CACYP1A2CYP3A4LMNATSHR | |
| SCHEMBL18193245 | 0.82 | CYP1A2 (0.59) | PIK3CACYP1A2CYP3A4LMNATSHR | |
| SCHEMBL12499329 | 0.78 | PIK3CA (0.72) | PIK3CACYP1A2CYP3A4LMNATSHR | |
| SCHEMBL12499830 | 0.74 | PIK3CA (0.77) | PIK3CAMTORPIK3CGPIK3CDPIK3CB | |
| SCHEMBL12498959 | 0.73 | PIK3CA (0.69) | PIK3CAMTORKMT2A | |
| SCHEMBL15386541 | 0.73 | PIK3CA (0.53) | PIK3CALMNAMTORPIK3CGMEN1 | |
| SCHEMBL12498527 | 0.72 | PIK3CA (0.62) | PIK3CACYP1A2CYP3A4TSHRMTOR | |
| SCHEMBL16308327 | 0.70 | PIK3CD (0.59) | PIK3CAPIK3CGPIK3CDPIK3CB | |
| SCHEMBL12498761 | 0.68 | PIK3CA (0.67) | PIK3CAMTORKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9481670-B2 | Triazine compounds | SPHAERA PHARMA PTE. LTD. (SG) | 2016-11-01 | — | — | US | disclosed |
| US-9481670-B2 | Triazine compounds | SPHAERA PHARMA PTE. LTD. (SG) | 2016-11-01 | — | — | US | disclosed |