Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 20/20 | 0.80 |
| ▸ | FAAH | O00519 | 9/20 | 0.61 |
| ▸ | AADAC | P22760 | 1/20 | 0.61 |
| ▸ | RAF1 | P04049 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16570117 | 1.00 | EPHX2 (0.80) | EPHX2FAAHAADACRAF1 | |
| SCHEMBL16578030 | 0.91 | EPHX2 (0.76) | EPHX2FAAHAADACRAF1 | |
| SCHEMBL18195156 | 0.91 | EPHX2 (0.76) | EPHX2FAAHAADACRAF1 | |
| SCHEMBL15611715 | 0.89 | EPHX2 (1.00) | EPHX2FAAHAADACRAF1 | |
| SCHEMBL12475045 | 0.89 | EPHX2 (1.00) | EPHX2FAAHAADACRAF1 | |
| SCHEMBL16570847 | 0.89 | EPHX2 (0.80) | EPHX2FAAHAADAC | |
| SCHEMBL18195163 | 0.87 | EPHX2 (0.78) | EPHX2FAAHAADACRAF1 | |
| SCHEMBL16570017 | 0.87 | EPHX2 (0.78) | EPHX2FAAHAADACRAF1 | |
| SCHEMBL18195151 | 0.87 | EPHX2 (0.70) | EPHX2FAAHAADACRAF1 | |
| SCHEMBL16569978 | 0.87 | EPHX2 (0.70) | EPHX2FAAHAADACRAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160318856-A1 | Substituted Urea eIF2alpha Kinase Activators | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-11-03 | — | — | US | disclosed |
| US-20160318856-A1 | Substituted Urea eIF2alpha Kinase Activators | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160318856-A1 | Substituted Urea eIF2alpha Kinase Activators | EIF2AK1, EIF2A, EIF4A2 | EPHX2 3905/4885FAAH 4078/4885AADAC 1796/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.