Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 20/20 | 0.74 |
| ▸ | ABL1 | P00519 | 13/20 | 0.74 |
| ▸ | HCK | P08631 | 7/20 | 0.68 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.67 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.67 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.67 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.67 |
| ▸ | PRKDC | P78527 | 4/20 | 0.67 |
| ▸ | EGFR | P00533 | 5/20 | 0.66 |
| ▸ | LCK | P06239 | 2/20 | 0.66 |
| ▸ | EPHA3 | P29320 | 2/20 | 0.66 |
| ▸ | CSK | P41240 | 2/20 | 0.66 |
| ▸ | KDR | P35968 | 3/20 | 0.65 |
| ▸ | MTOR | P42345 | 3/20 | 0.65 |
| ▸ | EPHB4 | P54760 | 3/20 | 0.65 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18196362 | 0.87 | SRC (0.69) | SRCABL1HCKPIK3CDPIK3CA | |
| SCHEMBL14574681 | 0.85 | SRC (1.00) | SRCABL1HCKPIK3CDPIK3CA | |
| SCHEMBL29389670 | 0.85 | SRC (1.00) | SRCABL1HCKPIK3CDPIK3CA | |
| SCHEMBL12436432 | 0.85 | SRC (0.74) | SRCABL1HCKPIK3CDPIK3CA | |
| SCHEMBL18196357 | 0.84 | SRC (0.72) | SRCABL1HCKPIK3CDPIK3CA | |
| SCHEMBL18196383 | 0.83 | SRC (0.77) | SRCABL1HCKPIK3CDPIK3CA | |
| SCHEMBL18196233 | 0.83 | SRC (0.72) | SRCABL1HCKPIK3CDPIK3CA | |
| SCHEMBL14574867 | 0.81 | SRC (1.00) | SRCABL1HCKPIK3CDPIK3CA | |
| SCHEMBL29391405 | 0.81 | SRC (1.00) | SRCABL1HCKPIK3CDPIK3CA | |
| SCHEMBL29390823 | 0.81 | SRC (1.00) | SRCABL1HCKPIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2528919-B1 | COMPOSITIONS AND METHODS FOR TREATING TOXOPLASMOSIS. CRYPTOSPORIDIOSIS AND OTHER APICOMPLEXAN PROTOZOAN RELATED DISEASES | UNIV WASHINGTON (US) | 2016-11-02 | — | — | EP | disclosed |