Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 20/20 | 0.83 |
| ▸ | CACNG2 | Q9Y698 | 2/20 | 0.46 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18190064 | 0.91 | GRIA1 (1.00) | GRIA1CACNG2 | |
| SCHEMBL18189834 | 0.88 | GRIA1 (1.00) | GRIA1CACNG2 | |
| SCHEMBL18190025 | 0.76 | GRIA1 (1.00) | GRIA1CACNG2 | |
| SCHEMBL18189760 | 0.72 | GRIA1 (1.00) | GRIA1 | |
| SCHEMBL18190112 | 0.72 | GRIA1 (1.00) | GRIA1CACNG2 | |
| SCHEMBL18189935 | 0.71 | GRIA1 (1.00) | GRIA1CACNG2 | |
| SCHEMBL18189804 | 0.67 | GRIA1 (1.00) | GRIA1 | |
| SCHEMBL18189975 | 0.66 | GRIA1 (1.00) | GRIA1CACNG2CYP2C8CYP2C9 | |
| SCHEMBL18190048 | 0.63 | GRIA1 (1.00) | GRIA1CACNG2CYP2C8CYP2C9 | |
| SCHEMBL18189780 | 0.63 | GRIA1 (0.60) | GRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016176457-A1 | IMIDAZOPYRAZINES AND PYRAZOLOPYRIMIDINES AND THEIR USE AS AMPA RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2016-11-03 | — | — | WO | disclosed |