Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.38 |
| ▸ | TACR2 | P21452 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 6/20 | 0.37 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.37 |
| ▸ | CCKBR | P32239 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3623022 | 0.91 | TACR2 (0.44) | TACR2TACR1CACNA1BCALCRLCCKBR | |
| SCHEMBL181885 | 0.90 | TACR2 (0.41) | TACR2TACR1CACNA1BCALCRLCCKBR | |
| SCHEMBL181884 | 0.90 | TACR2 (0.41) | TACR2TACR1CACNA1BCALCRLCCKBR | |
| SCHEMBL181920 | 0.88 | CALCRL (0.41) | TACR2TACR1CACNA1BCALCRLCCKBR | |
| SCHEMBL181919 | 0.88 | CALCRL (0.41) | TACR2TACR1CACNA1BCALCRLCCKBR | |
| SCHEMBL180948 | 0.87 | KMT2A (0.47) | CALCRLCCKBRKMT2AMAPK1 | |
| SCHEMBL180947 | 0.87 | KMT2A (0.47) | CALCRLCCKBRKMT2AMAPK1 | |
| SCHEMBL181580 | 0.83 | CALCRL (0.41) | TACR2TACR1CACNA1BCALCRLCCKBR | |
| SCHEMBL181581 | 0.83 | CALCRL (0.41) | TACR2TACR1CACNA1BCALCRLCCKBR | |
| SCHEMBL182025 | 0.83 | CALCRL (0.41) | TACR2TACR1CACNA1BCALCRLCCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401268-A1 | OXYINDOLE DERIVATIVES WITH MOTILIN RECEPTOR AGONISTIC ACTIVITY | RaQualia Pharma Inc (JP) | 2012-01-04 | — | — | EP | disclosed |