Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.48 |
| ▸ | CNR2 | P34972 | 4/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 11/20 | 0.48 |
| ▸ | PARP11 | Q9NR21 | 10/20 | 0.48 |
| ▸ | PARP1 | P09874 | 3/20 | 0.42 |
| ▸ | GRM5 | P41594 | 4/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1726570 | 0.81 | PARP10 (0.48) | PARP10PARP11PARP1GRM5PDPK1 | |
| SCHEMBL1725257 | 0.77 | PARP10 (0.59) | PARP10PARP11PARP1GRM5PDPK1 | |
| SCHEMBL1432009 | 0.77 | PARP10 (0.63) | PARP10PARP11PARP1GRM5PDPK1 | |
| SCHEMBL1727568 | 0.73 | PARP10 (0.58) | PARP10PARP11PARP1GRM5PDPK1 | |
| SCHEMBL10387824 | 0.73 | CNR1 (0.56) | CNR1CNR2 | |
| SCHEMBL10388169 | 0.73 | CNR1 (0.56) | CNR1CNR2 | |
| SCHEMBL793156 | 0.71 | PARP10 (0.77) | PARP10PARP11PARP1GRM5PDPK1 | |
| SCHEMBL1726500 | 0.71 | PARP10 (0.55) | PARP10PARP11PARP1GRM5PDPK1 | |
| SCHEMBL10387261 | 0.70 | NPC1 (0.63) | CNR1CNR2 | |
| SCHEMBL30549705 | 0.70 | PARP10 (0.68) | PARP10PARP11PARP1GRM5PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403846-B1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | HOFFMANN LA ROCHE (CH) | 2016-11-02 | — | — | EP | disclosed |