Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GSR | P00390 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18200406 | 0.98 | PDE10A (0.41) | PDE10ACYP1A2MEN1KMT2AMAPT | |
| SCHEMBL18201083 | 0.96 | PDE10A (0.40) | PDE10ACYP1A2MEN1KMT2AMAPT | |
| SCHEMBL18200407 | 0.95 | PDE10A (0.40) | PDE10ACYP1A2MEN1KMT2AMAPT | |
| SCHEMBL18201066 | 0.90 | PDE10A (0.43) | PDE10ACYP1A2MEN1KMT2AMAPT | |
| SCHEMBL18201063 | 0.89 | PDE10A (0.42) | PDE10ACYP1A2MEN1KMT2AMAPT | |
| SCHEMBL18200408 | 0.89 | MAPK10 (0.42) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL18201169 | 0.87 | PDE10A (0.41) | PDE10ACYP1A2MEN1KMT2AMAPT | |
| SCHEMBL18201025 | 0.85 | MAPK10 (0.43) | MEN1KMT2AMAPTMAPK10GSR | |
| SCHEMBL18201153 | 0.85 | PDE10A (0.42) | PDE10ACYP1A2MEN1KMT2AMAPT | |
| SCHEMBL18201141 | 0.84 | PDE10A (0.41) | PDE10ACYP1A2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3088392-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME | Heesung Material Ltd. (KR) | 2016-11-02 | — | — | EP | disclosed |