Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19308539 | 0.77 | FFAR1 (0.37) | FFAR1CA12CA2CA9GRM5 | |
| SCHEMBL19789970 | 0.75 | FFAR1 (0.39) | FFAR1KCNH2 | |
| SCHEMBL20004811 | 0.74 | FFAR1 (0.37) | FFAR1KCNH2CA12CA2CA9 | |
| SCHEMBL7859815 | 0.74 | FFAR1 (0.36) | FFAR1KCNH2CA12CA2CA9 | |
| SCHEMBL21564900 | 0.73 | GRM5 (0.52) | FFAR1KCNH2CA12CA2CA9 | |
| SCHEMBL18083040 | 0.72 | GRM5 (0.39) | AAK1FFAR1KCNH2CA12CA2 | |
| SCHEMBL7858993 | 0.72 | FFAR1 (0.46) | FFAR1 | |
| SCHEMBL19412660 | 0.71 | ESR1 (0.35) | AAK1FFAR1KCNH2CA12CA2 | |
| SCHEMBL19412658 | 0.71 | AR (0.35) | FFAR1KCNH2CA12CA2CA9 | |
| SCHEMBL12696828 | 0.71 | GRM5 (0.38) | AAK1FFAR1KCNH2CA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2688980-B1 | MESOGEN COMPOUNDS, LIQUID CRYSTALLINE MEDIA AND COMPONENTS FOR HIGH FREQUENCY TECHNOLOGY | MERCK PATENT GMBH (DE) | 2016-11-02 | — | — | EP | disclosed |