Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 18/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1817095 | 0.91 | ADORA1 (0.63) | ADORA1ADORA3ADORA2B | |
| SCHEMBL1817044 | 0.85 | ADORA1 (0.54) | ADORA1ADORA3ADORA2B | |
| SCHEMBL1820196 | 0.84 | ADORA1 (0.53) | ADORA1ADORA3ADORA2B | |
| SCHEMBL1818014 | 0.78 | ADORA1 (0.62) | ADORA1ADORA3ADORA2B | |
| SCHEMBL3306244 | 0.78 | ADORA1 (0.67) | ADORA1ADORA3ADORA2B | |
| SCHEMBL1818728 | 0.76 | ADORA1 (0.67) | ADORA1ADORA3ADORA2B | |
| SCHEMBL1818986 | 0.75 | ADORA1 (0.63) | ADORA1ADORA3ADORA2B | |
| SCHEMBL3301655 | 0.74 | ADORA1 (0.62) | ADORA1ADORA3ADORA2B | |
| SCHEMBL1817001 | 0.73 | ADORA1 (0.48) | ADORA1ADORA3ADORA2B | |
| SCHEMBL3307224 | 0.73 | ADORA1 (0.63) | ADORA1ADORA3ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2321296-A1 | SUBSTITUTED 5-AMINOPYRAZOLES AND USE THEREOF | Bayer Schering Pharma Aktiengesellschaft (DE) | 2011-05-18 | — | — | EP | disclosed |