Nitrogen

Nitrogen

SCHEMBL18203485

N#N.N#[N+]c1ccccc1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ CA4 P22748 3/20 0.35
▸ CA9 Q16790 3/20 0.35
▸ CA7 P43166 2/20 0.35
▸ CA14 Q9ULX7 2/20 0.35
▸ CA6 P23280 1/20 0.35
▸ ALDH1A1 P00352 2/20 0.33
▸ TSHR P16473 4/20 0.32
▸ CA1 P00915 2/20 0.30
▸ CA2 P00918 2/20 0.30
▸ TDP1 Q9NUW8 2/20 0.30
▸ CA12 O43570 1/20 0.30
▸ GLA P06280 1/20 0.30
▸ CA3 P07451 1/20 0.30
▸ LMNA P02545 1/20 0.30
▸ ALOX12 P18054 1/20 0.30
▸ ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL37140 0.97 — —
Water SCHEMBL11963057 0.93 — —
Fluoride Ion SCHEMBL6315266 0.93 — —
Hydrochloric Acid SCHEMBL3796670 0.93 CA4 (0.35) CA4CA9CA7CA14CA6
Bromide SCHEMBL11327569 0.93 CA4 (0.35) CA4CA9CA7CA14CA6
Ammonia Solution, Strong SCHEMBL23611461 0.93 — —
Hydrochloric Acid SCHEMBL8384341 0.93 — —
SCHEMBL7541997 0.93 — —
SCHEMBL11571044 0.93 — —
Iodide SCHEMBL18428509 0.93 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170158637-A1 Synthetic Processes of Carprofen CHEMWERTH, INC. 2017-06-08 — — US disclosed
US-9611217-B2 Synthetic processes of carprofen CHEMWERTH, INC. (US) 2017-04-04 — — US disclosed
US-20160326113-A1 Synthetic Processes of Carprofen CHEMWERTH, INC. 2016-11-10 — — US disclosed
EP-3091000-A1 SYNTHETIC PROCESS OF CARPROFEN ChemWerth, Inc. (US) 2016-11-09 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160326113-A1 Synthetic Processes of Carprofen CYP4F2, CYP4F3, CYP2J2 CA4 2587/4885CA9 4106/4885CA7 2959/4885
US-20170158637-A1 Synthetic Processes of Carprofen CYP4F2, CYP4F3, CYP2J2 CA4 2587/4885CA9 4106/4885CA7 2959/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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