Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18320 | 1.00 | GCK (0.74) | GCKGCKR | |
| SCHEMBL12078504 | 0.91 | GCK (0.76) | GCKGCKR | |
| SCHEMBL16424 | 0.91 | GCK (0.76) | GCKGCKR | |
| SCHEMBL17603 | 0.91 | GCK (0.76) | GCKGCKR | |
| SCHEMBL16196 | 0.91 | GCK (0.76) | GCKGCKR | |
| SCHEMBL17161 | 0.91 | GCK (0.76) | GCKGCKR | |
| SCHEMBL16961 | 0.91 | GCK (0.76) | GCKGCKR | |
| SCHEMBL16268 | 0.91 | GCK (0.76) | GCKGCKR | |
| SCHEMBL12078490 | 0.91 | GCK (0.76) | GCKGCKR | |
| SCHEMBL15200872 | 0.89 | GCKR (0.75) | GCKGCKR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012027261-A1 | SULFONYLPIPERAZINE DERIVATIVES THAT INTERACT WITH GLUCOKINASE REGULATORY PROTEIN FOR THE TREATMENT OF DIABETES | AMGEN INC. (US) | 2012-03-01 | — | — | WO | disclosed |