SCHEMBL1820485

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4551433	0.81	NR4A1 (0.62)	NR4A1SRD5A2TSHRALOX15FNTA
	SCHEMBL29583954	0.81	NR4A1 (0.62)	NR4A1SRD5A2TSHRALOX15FNTA
	SCHEMBL1468587	0.78	SRD5A2 (0.61)	NR4A1SRD5A2TSHRALOX15MAPK1
	SCHEMBL18249795	0.77	NR4A1 (0.61)	NR4A1SRD5A2TSHRALOX15FNTA
	SCHEMBL26231300	0.76	NR4A1 (0.50)	NR4A1SRD5A2TSHRALOX15FNTA
	SCHEMBL109128	0.75	TSHR (0.48)	NR4A1TSHRALOX15CASP1SMN1; SMN2
	SCHEMBL1822747	0.75	NR4A1 (0.62)	NR4A1SRD5A2TSHRALOX15FNTA
	SCHEMBL1819626	0.75	NR4A1 (0.62)	NR4A1SRD5A2TSHRALOX15FNTA
	SCHEMBL29872036	0.74	NR4A1 (0.49)	NR4A1SRD5A2TSHRALOX15FNTA
	SCHEMBL20446219	0.74	NR4A1 (0.49)	NR4A1SRD5A2TSHRALOX15FNTA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.