SCHEMBL1821005

SCHEMBL1821005

C[C@H](N)C(=O)OC(=O)[C@@H](N)CCCNC(=N)N

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NPY4R P50391 11/20 0.40
NPY1R P25929 6/20 0.40
NPY2R P49146 4/20 0.38
NPY5R Q15761 4/20 0.38
DPP7 Q9UHL4 1/20 0.37
SLC15A1 P46059 1/20 0.34
OTC P00480 1/20 0.34
ANPEP P15144 2/20 0.33
RNPEP Q9H4A4 2/20 0.33
ALOX15 P16050 1/20 0.33
DNPEP Q9ULA0 1/20 0.33
GNAI3 P08754 1/20 0.33
GNAO1 P09471 1/20 0.33
GNAI1 P63096 1/20 0.33
DDAH1 O94760 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9237239 0.92 NPY4R (0.39) NPY4RNPY1RNPY2RNPY5RDPP7
SCHEMBL28712062 0.92 NPY4R (0.39) NPY4RNPY1RNPY2RNPY5RDPP7
SCHEMBL288133 0.92 NPY4R (0.39) NPY4RNPY1RNPY2RNPY5RDPP7
SCHEMBL6762710 0.91 ANPEP (0.35) NPY4RNPY1RNPY2RNPY5RANPEP
Hydrochloric Acid SCHEMBL8040222 0.91 NPY4R (0.38) NPY4RNPY1RNPY2RNPY5RDPP7
Hydrochloric Acid SCHEMBL8039440 0.91 NPY4R (0.38) NPY4RNPY1RNPY2RNPY5RDPP7
Threonine SCHEMBL285577 0.90 NPY4R (0.36) NPY4RNPY1RNPY2RNPY5RDPP7
SCHEMBL15653883 0.90 NPY4R (0.41) NPY4RNPY1RNPY2RNPY5RDPP7
SCHEMBL323016 0.90 NPY4R (0.41) NPY4RNPY1RNPY2RNPY5RDPP7
SCHEMBL30531669 0.90 NPY4R (0.41) NPY4RNPY1RNPY2RNPY5RDPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024013258-A1 PRODUCTION OF CYSTEINE OR CYSTINE FROM SERINE IN FERMENTATION MEDIUM CYSBIO APS (DK) 2024-01-18 WO claimed
CN-110063313-A A kind of oxygenation bait and preparation method thereof with comprehensive high-tech attracting 威海猎屋渔具有限公司 2019-07-30 CN claimed
WO-2014026143-A1 CONJUGATED ANTI-MICROBIAL COMPOUNDS AND CONJUGATED ANTI-CANCER COMPOUNDS AND USES THEREOF PONO CORPORATION (US) 2014-02-13 WO claimed
EP-1562578-A1 THERAPEUTIC DELIVERY OF CARBON MONOXIDE TO EXTRACORPOREAL AND ISOLATED ORGANS Hemocorm Limited (GB) 2005-08-17 EP claimed
WO-2004045598-A1 THERAPEUTIC DELIVERY OF CARBON MONOXIDE TO EXTRACORPOREAL AND ISOLATED ORGANS HEMOCORM LIMITED (GB) 2004-06-03 WO claimed
US-20240185952-A1 DETECTING LOSS OF HETEROZYGOSITY IN HLA ALLELES USING MACHINE-LEARNING MODELS PERSONALIS INC (US) 2024-06-06 US disclosed
EP-4327327-A1 DETECTING LOSS OF HETEROZYGOSITY IN HLA ALLELES USING MACHINE-LEARNING MODELS Personalis, Inc. (US) 2024-02-28 EP disclosed
WO-2024013258-A1 PRODUCTION OF CYSTEINE OR CYSTINE FROM SERINE IN FERMENTATION MEDIUM CYSBIO APS (DK) 2024-01-18 WO disclosed
WO-2023121753-A1 BIOMOLECULE-POLYMER-PHARMACEUTICAL AGENT CONJUGATES FOR DELIVERING THE PHARMACEUTICAL AGENT MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2023-06-29 WO disclosed
CN-116286420-A Malate dehydrogenase 帝斯曼知识产权资产管理有限公司 2023-06-23 CN disclosed
EP-4186523-A1 A NOVEL METHOD FOR STABILIZATION OF A BIOPHARMACEUTICAL DRUG PRODUCT DURING PROCESSING Leukocare AG (DE) 2023-05-31 EP disclosed
CN-109689864-B Malate dehydrogenase 帝斯曼知识产权资产管理有限公司 2023-04-04 CN disclosed
EP-0852946-A2 Composition for cosmetic, pharmaceutical or dietetic use based on an amino-sugar and/or a polyhydroxylic acid De Paoli Ambrosi, Gianfranco (IT) 1998-07-15 EP disclosed
US-5514574-A Method of producing flavine nucleotides KYOWA HAKKO KOGYO CO., LTD. (JP) 1996-05-07 US disclosed
EP-0542240-A2 Process for producing flavine nucleotides KYOWA HAKKO KOGYO CO., LTD. (JP) 1993-05-19 EP disclosed
EP-0541716-A1 NOVEL METHODS AND COMPOSITIONS FOR TREATMENT OF ANGIOGENIC DISEASES REPLIGEN CORPORATION (US) 1993-05-19 EP disclosed
US-5189025-A Administering amino acid mixture BOARD OF REGENETS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1993-02-23 US disclosed
US-5162373-A Gut Atrophy Prevention, Ornithine, Methionine BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1992-11-10 US disclosed
WO-1992002240-A2 NOVEL METHODS AND COMPOSITIONS FOR TREATMENT OF ANGIOGENIC DISEASES REPLIGEN CORPORATION (US) 1992-02-20 WO disclosed
US-4988724-A Anticarcinogenic agents, antitumor agents, amino acids and citrulline and ornithine; arginine-free; antitumor and -carcinogenic agents BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1991-01-29 US disclosed