Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 6/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | OTUD7B | Q6GQQ9 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16087580 | 1.00 | PTH1R (0.41) | PTH1RSCN9ACCNT1CDK9HCRTR1 | |
| SCHEMBL16302254 | 0.93 | PTH1R (0.37) | PTH1R | |
| SCHEMBL848059 | 0.92 | PTH1R (0.43) | PTH1RSCN9ACCNT1CDK9KIT | |
| SCHEMBL848058 | 0.92 | PTH1R (0.43) | PTH1RSCN9ACCNT1CDK9KIT | |
| SCHEMBL879962 | 0.91 | PTH1R (0.43) | PTH1RSCN9ACCNT1CDK9HCRTR1 | |
| SCHEMBL848151 | 0.90 | PTH1R (0.42) | PTH1RSCN9ACCNT1CDK9KIT | |
| SCHEMBL848149 | 0.90 | PTH1R (0.42) | PTH1RSCN9ACCNT1CDK9KIT | |
| SCHEMBL13555176 | 0.89 | PTH1R (0.43) | PTH1RSCN9ACCNT1CDK9MMP2 | |
| SCHEMBL847449 | 0.88 | PTH1R (0.45) | PTH1RSCN9AHCRTR1HCRTR2MMP2 | |
| SCHEMBL847448 | 0.88 | PTH1R (0.45) | PTH1RSCN9AHCRTR1HCRTR2MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9487517-B2 | Spiroimidazolone derivative | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2016-11-08 | — | — | US | disclosed |