⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6232290 | 0.91 | — | — | |
| SCHEMBL6235137 | 0.89 | — | — | |
| SCHEMBL7400171 | 0.89 | — | — | |
| SCHEMBL4115861 | 0.84 | — | — | |
| SCHEMBL2362303 | 0.82 | — | — | |
| SCHEMBL7406252 | 0.80 | — | — | |
| SCHEMBL7517207 | 0.76 | — | — | |
| SCHEMBL6260329 | 0.74 | — | — | |
| SCHEMBL7402488 | 0.74 | — | — | |
| SCHEMBL3195823 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9730940-B2 | Purine inhibitors of human phosphatidylinositol 3-kinase delta | MERCK SHARP & DOHME (US) | 2017-08-15 | — | — | US | claimed |
| EP-1660493-A1 | PEPTIDYL HETEROCYCLIC KETONE DERIVATIVES AND PREPARATION PROCESSES | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-05-31 | — | — | EP | claimed |
| US-20050059607-A1 | Process for preparing peptidyl heterocyclic ketone derivatives | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-03-17 | — | — | US | claimed |
| WO-2005023804-A1 | PEPTIDYL HETEROCYCLIC KETONE DERIVATIVES AND PREPARATION PROCESSES | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-03-17 | — | — | WO | claimed |
| US-20030008829-A1 | Peptidyl heterocyclic ketones useful as tryptase inhibitors | COSTANZO MICHAEL J (US) | 2003-01-09 | — | — | US | claimed |
| EP-1147097-A1 | PEPTIDYL HETEROCYCLIC KETONES USEFUL AS TRYPTASE INHIBITORS | Ortho-Mcneil Pharmaceutical, Inc. (US) | 2001-10-24 | — | — | EP | claimed |
| WO-2000044733-A1 | PEPTIDYL HETEROCYCLIC KETONES USEFUL AS TRYPTASE INHIBITORS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2000-08-03 | — | — | WO | claimed |
| US-5283166-A | Yellow dye-forming coupler and silver halide color photographic light-sensitive material containing the same | FUJI PHOTO FILM CO., LTD. (JP) | 1994-02-01 | — | — | US | claimed |
| JP-4344640-A | — | — | None | — | — | JP | disclosed |
| US-11753385-B2 | Method for producing kakeromycin and derivatives thereof | OP BIO FACTORY CO., LTD. (JP) | 2023-09-12 | — | — | US | disclosed |
| US-20220024883-A1 | METHOD FOR PRODUCING KAKEROMYCIN AND DERIVATIVES THEREOF | OP BIO FACTORY CO., LTD. (JP) | 2022-01-27 | — | — | US | disclosed |
| EP-3263572-B1 | METHOD FOR PRODUCING KAKEROMYCIN AND DERIVATIVES THEREOF | SEED RES INSTITUTE CO LTD (JP) | 2021-12-15 | — | — | EP | disclosed |
| US-11155526-B2 | Method for producing kakeromycin and derivatives thereof | OP BIO FACTORY CO., LTD. (JP) | 2021-10-26 | — | — | US | disclosed |
| US-10703732-B2 | Method for producing kakeromycin and derivatives thereof | OP BIO FACTORY CO., LTD. (JP) | 2020-07-07 | — | — | US | disclosed |
| US-5283166-A | Yellow dye-forming coupler and silver halide color photographic light-sensitive material containing the same | FUJI PHOTO FILM CO., LTD. (JP) | 1994-02-01 | — | — | US | disclosed |
| EP-0578249-A2 | Silver halide color photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1994-01-12 | — | — | EP | disclosed |
| WO-1993004142-A1 | STABILIZED COMPLEX LIGANDS AND THEIR USE IN LIQUID CRYSTAL DISPLAYS | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-04 | — | — | WO | disclosed |
| EP-0528415-A1 | Stabilized complex ligands and their use in liquid crystal displays | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-02-24 | — | — | EP | disclosed |
| JP-H04344640-A | YELLOW DYE FORMING COUPLER AND SILVER HALIDE COLOR PHOTOGRAPHIC SENSITIVE MATERIAL CONTAINING SAME | FUJI PHOTO FILM CO LTD | 1992-12-01 | — | — | JP | disclosed |
| US-3989685-A | FROM PENICILLIN-1-OXIDE | SHINOGI & CO., LTD. (JA) | 1976-11-02 | — | — | US | disclosed |