Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18214704 | 0.83 | TP53 (0.51) | BRPF1KMT2AMEN1RXFP1KDM4E | |
| SCHEMBL18214692 | 0.81 | TP53 (0.46) | KMT2AMEN1RXFP1KDM4EALDH1A1 | |
| SCHEMBL18214707 | 0.81 | TP53 (0.46) | KMT2AMEN1RXFP1L3MBTL1KDM4E | |
| SCHEMBL7904385 | 0.72 | GRIN2D (0.52) | BRPF1KMT2AMEN1L3MBTL1KDM4E | |
| SCHEMBL7898918 | 0.69 | GRIN2D (0.48) | BRPF1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL7905039 | 0.69 | GRIN2D (0.50) | BRPF1KMT2AMEN1THRBRXFP1 | |
| SCHEMBL7907679 | 0.69 | GRIN2D (0.47) | BRPF1KMT2AMEN1 | |
| SCHEMBL7908241 | 0.68 | GRIN2D (0.46) | BRPF1KMT2AMEN1RXFP1ALDH1A1 | |
| SCHEMBL7905764 | 0.68 | GRIN2D (0.46) | BRPF1KMT2AMEN1L3MBTL1KDM4E | |
| SCHEMBL14826760 | 0.68 | GRIN2D (0.46) | BRPF1KMT2AMEN1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2404922-B1 | QUINOXALINE COMPOUNDS | ASTELLAS PHARMA INC (JP) | 2016-11-09 | — | — | EP | disclosed |