Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 4/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.40 |
| ▸ | PRKG1 | Q13976 | 3/20 | 0.40 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.40 |
| ▸ | PRKACA | P17612 | 2/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | AKT1 | P31749 | 2/20 | 0.40 |
| ▸ | AKT2 | P31751 | 2/20 | 0.40 |
| ▸ | GSK3A | P49840 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.40 |
| ▸ | PRKX | P51817 | 2/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.40 |
| ▸ | PRKG2 | Q13237 | 2/20 | 0.40 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.40 |
| ▸ | CDC42BPA | Q5VT25 | 2/20 | 0.40 |
| ▸ | HIPK4 | Q8NE63 | 2/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16548163 | 1.00 | CASR (0.41) | CASRROCK1PRKG1RPS6KA5PRKACA | |
| Hydrochloric Acid SCHEMBL16540254 | 0.99 | CASR (0.40) | CASRROCK1PRKG1RPS6KA5PRKACA | |
| SCHEMBL17945890 | 0.93 | CASR (0.41) | CASRROCK1PRKG1PRKACARPS6KB1 | |
| Hydrochloric Acid SCHEMBL16540215 | 0.92 | CASR (0.40) | CASRROCK1PRKG1PRKACARPS6KB1 | |
| SCHEMBL16548234 | 0.91 | POLB (0.41) | CASRROCK1PRKG1RPS6KA5PRKACA | |
| SCHEMBL16548158 | 0.91 | CASR (0.41) | CASRROCK1PRKG1RPS6KA5PRKACA | |
| SCHEMBL16541124 | 0.91 | POLB (0.41) | CASRROCK1PRKG1RPS6KA5PRKACA | |
| SCHEMBL16548327 | 0.91 | PPARG (0.40) | PPARGLMNA | |
| SCHEMBL16548190 | 0.91 | CASR (0.39) | CASRROCK1PRKG1RPS6KA5PRKACA | |
| SCHEMBL17950569 | 0.91 | CASR (0.39) | CASRROCK1PRKG1RPS6KA5PRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9493396-B2 | Substituted naphthalene compounds as calcium sensing receptor modulators | LUPIN ATLANTIS HOLDINGS SA (CH) | 2016-11-15 | — | — | US | disclosed |