Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 14/20 | 0.54 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.37 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16548225 | 1.00 | CASR (0.54) | CASRMDM2ENPP1SLC6A4TRPA1 | |
| Hydrochloric Acid SCHEMBL17939884 | 0.99 | CASR (0.53) | CASRMDM2ENPP1SLC6A4TRPA1 | |
| SCHEMBL16548304 | 0.91 | CASR (0.45) | CASRSLC6A4TRPA1 | |
| Hydrochloric Acid SCHEMBL17939903 | 0.90 | CASR (0.45) | CASRSLC6A4TRPA1 | |
| SCHEMBL17945902 | 0.89 | CASR (0.54) | CASRSLC6A4 | |
| SCHEMBL18215375 | 0.89 | CASR (0.54) | CASRSLC6A4 | |
| Hydrochloric Acid SCHEMBL17939848 | 0.88 | CASR (0.53) | CASRSLC6A4 | |
| SCHEMBL16548305 | 0.87 | KIT (0.39) | CASR | |
| Hydrochloric Acid SCHEMBL17939951 | 0.86 | KIT (0.39) | CASR | |
| SCHEMBL16548219 | 0.86 | CASR (0.41) | CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9493396-B2 | Substituted naphthalene compounds as calcium sensing receptor modulators | LUPIN ATLANTIS HOLDINGS SA (CH) | 2016-11-15 | — | — | US | disclosed |