Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 10/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | PPARA | Q07869 | 4/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | PFKFB3 | Q16875 | 3/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17945927 | 1.00 | CASR (0.41) | CASRSLC6A2SLC6A4PPARGPPARA | |
| Hydrochloric Acid SCHEMBL17939837 | 0.99 | CASR (0.41) | CASRSLC6A2SLC6A4PPARGPPARA | |
| SCHEMBL17945094 | 0.88 | GRM2 (0.40) | CASRPPARGPPARAGRM2PFKFB3 | |
| SCHEMBL16548307 | 0.88 | MEN1 (0.47) | CASRSLC6A2SLC6A4PFKFB3ROCK2 | |
| Hydrochloric Acid SCHEMBL17939795 | 0.88 | GRM2 (0.39) | CASRPPARGPPARAGRM2PFKFB3 | |
| Hydrochloric Acid SCHEMBL17939978 | 0.87 | MEN1 (0.46) | CASRSLC6A2SLC6A4PFKFB3ROCK2 | |
| SCHEMBL17945540 | 0.87 | CASR (0.45) | CASRSLC6A2SLC6A4PFKFB3ROCK2 | |
| SCHEMBL17950564 | 0.87 | CASR (0.42) | CASRSLC6A2SLC6A4PFKFB3ROCK2 | |
| Hydrochloric Acid SCHEMBL17939817 | 0.86 | CASR (0.44) | CASRSLC6A2SLC6A4PFKFB3ROCK2 | |
| SCHEMBL16548161 | 0.85 | CASR (0.59) | CASRSLC6A2SLC6A4ROCK2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9493396-B2 | Substituted naphthalene compounds as calcium sensing receptor modulators | LUPIN ATLANTIS HOLDINGS SA (CH) | 2016-11-15 | — | — | US | disclosed |