Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.66 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 4/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18215471 | 1.00 | CYP1A2 (0.74) | CYP1A2HSD17B10JAK2EGFRDRD4 | |
| SCHEMBL2643532 | 1.00 | CYP1A2 (0.74) | CYP1A2HSD17B10JAK2EGFRDRD4 | |
| SCHEMBL7426368 | 0.85 | CYP1A2 (1.00) | CYP1A2HSD17B10DRD4DRD3DRD2 | |
| SCHEMBL13995842 | 0.83 | HSD17B10 (0.71) | CYP1A2HSD17B10DRD4DRD3DRD2 | |
| SCHEMBL12214779 | 0.81 | CYP1A2 (0.51) | CYP1A2HSD17B10JAK2EGFRHTT | |
| SCHEMBL18215470 | 0.81 | HSD17B10 (0.73) | CYP1A2HSD17B10EGFRDRD4DRD3 | |
| SCHEMBL2645035 | 0.81 | HSD17B10 (0.73) | CYP1A2HSD17B10EGFRDRD4DRD3 | |
| SCHEMBL31133079 | 0.81 | HSD17B10 (0.73) | CYP1A2HSD17B10EGFRDRD4DRD3 | |
| SCHEMBL18215418 | 0.81 | HSD17B10 (0.73) | CYP1A2HSD17B10EGFRDRD4DRD3 | |
| SCHEMBL18215458 | 0.80 | CYP1A2 (0.50) | CYP1A2HSD17B10JAK2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3292102-B1 | ISOINDOLINONES, PROCESSES FOR THE PRODUCTION OF CHIRAL DERIVATIVES THEREOF AND USE THEREOF | UNIV DEGLI STUDI DI SALERNO (IT) | 2021-09-08 | — | — | EP | disclosed |
| WO-2016178140-A1 | ISOINDOLINONES, PROCESSES FOR THE PRODUCTION OF CHIRAL DERIVATIVES THEREOF AND USE THEREOF | UNIVERSITA' DEGLI STUDI DI SALERNO (IT) | 2016-11-10 | — | — | WO | disclosed |