Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 4/20 | 0.39 |
| ▸ | CA6 | P23280 | 4/20 | 0.39 |
| ▸ | CA7 | P43166 | 4/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA4 | P22748 | 3/20 | 0.37 |
| ▸ | CA5A | P35218 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CA3 | P07451 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18217828 | 0.81 | CA12 (0.58) | CYP2C19CYP2C9CA12CA6CA7 | |
| SCHEMBL13079437 | 0.79 | CYP2C9 (0.38) | CYP2C19CYP2C9CA12CA6CA7 | |
| SCHEMBL9921420 | 0.78 | CA12 (0.62) | CYP2C19CYP2C9CA12CA6CA7 | |
| SCHEMBL23489524 | 0.76 | CA12 (0.65) | CYP2C19CYP2C9CA12CA6CA7 | |
| SCHEMBL23489569 | 0.76 | CA12 (0.65) | CYP2C19CYP2C9CA12CA6CA7 | |
| SCHEMBL13330251 | 0.74 | CYP2C19 (0.56) | CYP2C19CYP2C9CA12CA6CA7 | |
| SCHEMBL23489527 | 0.74 | CYP2C19 (0.56) | CYP2C19CYP2C9CA12CA6CA7 | |
| SCHEMBL600153 | 0.74 | CYP2C19 (0.56) | CYP2C19CYP2C9CA12CA6CA7 | |
| SCHEMBL18217838 | 0.74 | BLM (0.31) | HSD17B10 | |
| SCHEMBL18217836 | 0.74 | CA12 (0.40) | CYP2C19CYP2C9CA12CA6CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180162987-A1 | DEGRADABLE POLYURETHANES AND COMPOSITES THEREOF | ADESSO ADVANCED MATERIALS WUHU CO., LTD. (CN) | 2018-06-14 | — | — | US | disclosed |
| WO-2016177307-A1 | DEGRADABLE POLYURETHANES AND COMPOSITES THEREOF | ADESSO ADVANCED MATERIALS WUXI CO., LTD. (CN) | 2016-11-10 | — | — | WO | disclosed |