Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 18/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1812954 | 0.84 | AR (0.55) | AR | |
| SCHEMBL1813687 | 0.84 | AR (0.55) | AR | |
| SCHEMBL1812956 | 0.84 | AR (0.55) | AR | |
| SCHEMBL1817139 | 0.83 | AR (0.44) | AR | |
| SCHEMBL1817136 | 0.83 | AR (0.44) | AR | |
| SCHEMBL1816762 | 0.81 | AR (0.41) | ARJAK2TYK2 | |
| SCHEMBL1814084 | 0.77 | HTR2A (0.41) | AR | |
| SCHEMBL1812527 | 0.76 | AR (0.57) | AR | |
| SCHEMBL1813547 | 0.76 | AR (0.57) | AR | |
| SCHEMBL1812528 | 0.76 | AR (0.57) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011051540-A1 | ANDROGEN RECEPTOR MODULATING COMPOUNDS | ORION CORPORATION (FI) | 2011-05-05 | — | — | WO | disclosed |