Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16324856 | 0.85 | CYP19A1 (0.31) | — | |
| SCHEMBL27466995 | 0.82 | CYP1A1 (0.30) | — | |
| SCHEMBL4050748 | 0.78 | — | — | |
| SCHEMBL1148591 | 0.74 | — | — | |
| SCHEMBL30724678 | 0.73 | — | — | |
| SCHEMBL16964335 | 0.71 | — | — | |
| SCHEMBL16964480 | 0.70 | MGAM (0.39) | — | |
| SCHEMBL28204887 | 0.69 | — | — | |
| SCHEMBL28457553 | 0.69 | CYP19A1 (0.38) | — | |
| SCHEMBL29299953 | 0.67 | NOTUM (0.33) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2493297-A1 | HETEROCYCLE AMIDE T-TYPE CALCIUM CHANNEL ANTAGONISTS | Merck Sharp & Dohme Corp. (US) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011053542-A1 | HETEROCYCLE AMIDE T-TYPE CALCIUM CHANNEL ANTAGONISTS | MERCK SHARP & DOHME CORP. (US) | 2011-05-05 | — | — | WO | disclosed |