Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 8/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1822654 | 1.00 | AKR1C3 (0.46) | AKR1C3APEX1RXRARXRBNR4A2 | |
| SCHEMBL1822661 | 0.85 | AKR1C3 (0.46) | AKR1C3APEX1RXRARXRBNR4A2 | |
| SCHEMBL1822659 | 0.85 | AKR1C3 (0.46) | AKR1C3APEX1RXRARXRBNR4A2 | |
| SCHEMBL1823826 | 0.79 | HPGD (0.49) | AKR1C3APEX1RXRARXRBNR4A2 | |
| SCHEMBL1823823 | 0.79 | HPGD (0.49) | AKR1C3APEX1RXRARXRBNR4A2 | |
| SCHEMBL1826512 | 0.77 | CYP2A6 (0.43) | SMN1; SMN2PLA2G10BACE1 | |
| SCHEMBL1826825 | 0.73 | PPARG (0.36) | AKR1C3APEX1RXRARXRBNR4A2 | |
| SCHEMBL379474 | 0.73 | AKR1C3 (0.50) | AKR1C3APEX1RXRARXRBNR4A2 | |
| SCHEMBL379475 | 0.73 | AKR1C3 (0.50) | AKR1C3APEX1RXRARXRBNR4A2 | |
| SCHEMBL1801707 | 0.72 | PLK1 (0.43) | SMN1; SMN2PLA2G10BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1854804-B1 | Heterocyclic metallocene compounds and use thereof in catalyst systems for producing olefin polymers | BASELL POLYOLEFINE GMBH (DE) | 2011-05-04 | — | — | EP | disclosed |
| EP-1854804-A1 | Heterocyclic metallocene compounds and use thereof in catalyst systems for producing olefin polymers | Basell Polyolefine GmbH (DE) | 2007-11-14 | — | — | EP | disclosed |
| EP-1854804-A1 | Heterocyclic metallocene compounds and use thereof in catalyst systems for producing olefin polymers | Basell Polyolefine GmbH (DE) | 2007-11-14 | — | — | EP | disclosed |
| CN-1280300-C | Heterocyclic metallocene compounds and use thereof in catalyst systems for producing olefin polymers | BASELL TECHNOLOGY CO BV (NL) | 2006-10-18 | — | — | CN | disclosed |
| US-7112638-B2 | Hetero cyclic metallocene compounds and use thereof in catalyst system for producing olefin polymers | BASELL POLYOLEFINE GMBH (DE) | 2006-09-26 | — | — | US | disclosed |
| US-20030036612-A1 | Hetero cyclic metallocene compounds and use thereof in catalyst system for producing olefin polymers | BASELL POLYOLEFINE GMBH (DE) | 2003-02-20 | — | — | US | disclosed |
| EP-1157027-A1 | HETEROCYCLIC METALLOCENE COMPOUNDS AND USE THEREOF IN CATALYST SYSTEMS FOR PRODUCING OLEFIN POLYMERS | Basell Technology Company B.V. (NL) | 2001-11-28 | — | — | EP | disclosed |
| WO-2001047939-A1 | HETEROCYCLIC METALLOCENE COMPOUNDS AND USE THEREOF IN CATALYST SYSTEMS FOR PRODUCING OLEFIN POLYMERS | BASELL TECHNOLOGY COMPANY B.V. (NL) | 2001-07-05 | — | — | WO | disclosed |