Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 7/20 | 0.64 |
| ▸ | SLC1A1 | P43005 | 7/20 | 0.64 |
| ▸ | SLC1A3 | P43003 | 6/20 | 0.64 |
| ▸ | GRIK1 | P39086 | 5/20 | 0.64 |
| ▸ | GRIK2 | Q13002 | 5/20 | 0.64 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | BHMT | Q93088 | 1/20 | 0.44 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3383446 | 1.00 | SLC1A2 (0.64) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL839403 | 1.00 | SLC1A2 (0.64) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL18229129 | 1.00 | SLC1A2 (0.64) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| Hydrochloric Acid SCHEMBL3991878 | 0.98 | SLC1A2 (0.62) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| Hydrochloric Acid SCHEMBL28460968 | 0.98 | SLC1A2 (0.62) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| Hydrochloric Acid SCHEMBL5612600 | 0.98 | SLC1A2 (0.62) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| Hydrochloric Acid SCHEMBL3999984 | 0.98 | SLC1A2 (0.62) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL28900373 | 0.88 | SLC1A2 (0.67) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL28900372 | 0.88 | SLC1A2 (0.67) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL28900379 | 0.86 | SLC1A2 (0.68) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10738083-B2 | Influenza virus neutralizing peptidomimetic compounds | JANSSEN VACCINES & PREVENTION B.V. (NL) | 2020-08-11 | — | — | US | claimed |
| US-20180118788-A1 | INFLUENZA VIRUS NEUTRALIZING PEPTIDOMIMETIC COMPOUNDS | JANSSEN VACCINES & PREVENTION B.V. (NL) | 2018-05-03 | — | — | US | claimed |
| EP-3294753-A1 | INFLUENZA VIRUS NEUTRALIZING PEPTIDOMIMETIC COMPOUNDS | Janssen Vaccines & Prevention B.V. (NL) | 2018-03-21 | — | — | EP | claimed |
| WO-2016180826-A1 | INFLUENZA VIRUS NEUTRALIZING PEPTIDOMIMETIC COMPOUNDS | JANSSEN VACCINES & PREVENTION B.V. (NL) | 2016-11-17 | — | — | WO | claimed |
| CN-107592865-B | Peptidomimetic compounds for neutralizing influenza viruses | 扬森疫苗与预防公司 | 2022-01-25 | — | — | CN | disclosed |
| US-10738083-B2 | Influenza virus neutralizing peptidomimetic compounds | JANSSEN VACCINES & PREVENTION B.V. (NL) | 2020-08-11 | — | — | US | disclosed |
| US-20180118788-A1 | INFLUENZA VIRUS NEUTRALIZING PEPTIDOMIMETIC COMPOUNDS | JANSSEN VACCINES & PREVENTION B.V. (NL) | 2018-05-03 | — | — | US | disclosed |
| EP-3294753-A1 | INFLUENZA VIRUS NEUTRALIZING PEPTIDOMIMETIC COMPOUNDS | Janssen Vaccines & Prevention B.V. (NL) | 2018-03-21 | — | — | EP | disclosed |
| WO-2016180826-A1 | INFLUENZA VIRUS NEUTRALIZING PEPTIDOMIMETIC COMPOUNDS | JANSSEN VACCINES & PREVENTION B.V. (NL) | 2016-11-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10738083-B2 | Influenza virus neutralizing peptidomimetic compounds | ANPEP, NEU1, NGLY1 | SLC1A2 3932/4885SLC1A1 2249/4885SLC1A3 1971/4885 |
| US-20180118788-A1 | INFLUENZA VIRUS NEUTRALIZING PEPTIDOMIMETIC COMPOUNDS | ANPEP, NEU1, NGLY1 | SLC1A2 3932/4885SLC1A1 2249/4885SLC1A3 1971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.