Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TACR3 | P29371 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1829839 | 1.00 | EPHX2 (0.51) | EPHX2LMNATACR3TSHRHPGD | |
| SCHEMBL1824200 | 0.96 | EPHX2 (0.47) | EPHX2LMNATACR3TSHRHPGD | |
| SCHEMBL12310518 | 0.85 | HPGD (0.56) | EPHX2TACR3TSHRHPGDCD274 | |
| SCHEMBL12310320 | 0.85 | HPGD (0.56) | EPHX2TACR3TSHRHPGDCD274 | |
| SCHEMBL12310309 | 0.82 | TACR3 (0.48) | LMNATACR3TSHRHPGDCD274 | |
| SCHEMBL12260234 | 0.81 | TSHR (0.58) | TSHRALDH1A1CYP2C19 | |
| SCHEMBL12310321 | 0.81 | TSHR (0.58) | TSHRALDH1A1CYP2C19 | |
| SCHEMBL19919962 | 0.80 | TSHR (0.56) | TSHRALDH1A1CYP2C19 | |
| SCHEMBL12310519 | 0.80 | TSHR (0.56) | TSHRALDH1A1CYP2C19 | |
| SCHEMBL12310322 | 0.80 | TSHR (0.56) | TSHRALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2498782-A1 | CRYSTALLINE FORMS OF NEUROTROPHIN MIMETIC COMPOUNDS AND THEIR SALTS | Pharmatrophix Inc. (US) | 2012-09-19 | — | — | EP | disclosed |
| WO-2011060262-A1 | CRYSTALLINE FORMS OF NEUROTROPHIN MIMETIC COMPOUNDS AND THEIR SALTS | PHARMATROPHIX, INC. (US) | 2011-05-19 | — | — | WO | disclosed |