Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18230217 | 0.85 | TRPV1 (0.54) | SMN1; SMN2KDM4EHTTALDH1A1RXFP1 | |
| SCHEMBL18230291 | 0.85 | ADORA1 (0.57) | SMN1; SMN2KDM4EHTTALDH1A1RXFP1 | |
| SCHEMBL18230523 | 0.84 | TRPV1 (0.57) | SMN1; SMN2KDM4EHTTALDH1A1NPC1 | |
| SCHEMBL18230442 | 0.83 | TRPV1 (0.52) | SMN1; SMN2KDM4EHTTALDH1A1RXFP1 | |
| SCHEMBL18230379 | 0.82 | ADORA2A (0.71) | SMN1; SMN2HTTNPC1LMNAMEN1 | |
| SCHEMBL18230521 | 0.82 | TRPV1 (0.59) | SMN1; SMN2KDM4EHTTALDH1A1NPC1 | |
| SCHEMBL18230429 | 0.82 | TRPV1 (0.52) | SMN1; SMN2KDM4EHTTALDH1A1LMNA | |
| SCHEMBL29078713 | 0.81 | DHODH (0.56) | DHODHALDH1A1NPC1LMNAMEN1 | |
| SCHEMBL18230320 | 0.81 | ADORA2A (0.70) | SMN1; SMN2KDM4EHTTALDH1A1RXFP1 | |
| SCHEMBL18230280 | 0.81 | TRPV1 (0.58) | SMN1; SMN2KDM4EHTTALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016183173-A1 | ANTIPARASITIC COMPOUNDS | Avista Pharma Solutions (US) | 2016-11-17 | — | — | WO | disclosed |
| WO-2016183173-A1 | ANTIPARASITIC COMPOUNDS | Avista Pharma Solutions (US) | 2016-11-17 | — | — | WO | disclosed |