Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14899132 | 0.87 | GCK (0.48) | GCKGCKR | |
| SCHEMBL33220 | 0.85 | GCK (0.66) | GCKGCKR | |
| SCHEMBL12093429 | 0.85 | GCK (0.47) | GCKGCKR | |
| SCHEMBL12089559 | 0.84 | GCK (0.54) | GCKGCKR | |
| SCHEMBL18509 | 0.82 | GCK (0.66) | GCKGCKR | |
| SCHEMBL17845 | 0.80 | GCKR (0.57) | GCKGCKR | |
| SCHEMBL14899167 | 0.78 | GCKR (0.59) | GCKGCKR | |
| SCHEMBL14899156 | 0.77 | GCK (0.58) | GCKGCKR | |
| SCHEMBL14899172 | 0.77 | GCK (0.58) | GCKGCKR | |
| SCHEMBL12089617 | 0.76 | GCK (0.72) | GCKGCKR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012027261-A1 | SULFONYLPIPERAZINE DERIVATIVES THAT INTERACT WITH GLUCOKINASE REGULATORY PROTEIN FOR THE TREATMENT OF DIABETES | AMGEN INC. (US) | 2012-03-01 | — | — | WO | disclosed |