⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17358793 | 0.97 | — | — | |
| SCHEMBL17432730 | 0.97 | — | — | |
| SCHEMBL17371322 | 0.97 | — | — | |
| SCHEMBL15871304 | 0.89 | — | — | |
| SCHEMBL18211010 | 0.84 | — | — | |
| SCHEMBL1904137 | 0.76 | — | — | |
| SCHEMBL190332 | 0.72 | — | — | |
| SCHEMBL13528155 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL7337523 | 0.69 | — | — | |
| SCHEMBL17479976 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170274073-A1 | METHODS OF TREATING CANCER USING PD-1 AXIS BINDING ANTAGONISTS AND IL-17 BINDING ANTAGONISTS | GENENTECH, INC. (US) | 2017-09-28 | — | — | US | disclosed |
| US-20160331750-A1 | METHODS FOR TREATMENT OF LYMPHOMAS WITH MUTATIONS IN CELL CYCLE GENES | MEMORIAL SLOAN KETTERING CANCER CENTER (US) | 2016-11-17 | — | — | US | disclosed |
| US-9493544-B2 | Von willebrand factor- and factor VIII-polymer conjugates having a releasable linkage | NEKTAR THERAPEUTICS (US) | 2016-11-15 | — | — | US | disclosed |