Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.52 |
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.43 |
| ▸ | PLA2G7 | Q13093 | 4/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | TTR | P02766 | 2/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17884222 | 0.92 | AR (0.52) | ARIDO1PPARGPPARAS1PR1 | |
| SCHEMBL14656196 | 0.89 | AR (0.50) | ARIDO1PPARGPPARAS1PR1 | |
| SCHEMBL29918343 | 0.89 | AR (0.50) | ARIDO1PPARGPPARAS1PR1 | |
| SCHEMBL14670088 | 0.88 | AR (0.49) | ARIDO1PPARGPPARAS1PR1 | |
| SCHEMBL17884223 | 0.88 | AR (0.52) | ARIDO1PPARGPPARAS1PR1 | |
| SCHEMBL29918384 | 0.85 | IDO1 (0.50) | ARIDO1PPARGPPARAS1PR1 | |
| SCHEMBL875664 | 0.85 | IDO1 (0.50) | ARIDO1PPARGPPARAS1PR1 | |
| SCHEMBL29918437 | 0.85 | AR (0.67) | ARPLA2G7 | |
| SCHEMBL875787 | 0.85 | AR (0.67) | ARPLA2G7 | |
| SCHEMBL932893 | 0.83 | IDO1 (0.61) | IDO1S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016180247-A1 | BICYCLIC COMPOUND USED AS AN LP-PLA2 INHIBITOR, AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF | 中国科学院上海药物研究所 | 2016-11-17 | — | — | WO | disclosed |